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Joint SUPPORT is a food supplement of glucosamine, MSM, hyaluronic acid and plant extracts, suitable for adult sportsmen who practice intense physical activities. JOINT SUPPORT is indicated in those cases where it is necessary to support joint function (Curcuma, Boswellia) and to contrast localized states of tension (Boswellia).
SCIENTIFIC LITERATURE
Yoshimura, M., Sakamoto, K., Yamamoto, T., Ishida, K., Yamaguchi, H., & Nagaoka, I. (2009). Evaluation of the effect of glucosamine administration on biomarkers for cartilage and bone metabolism in soccer players. International journal of molecular medicine, 24(4), 487-494.
Momomura, R., Naito, K., Igarashi, M., Watari, T., Terakado, A., Oike, S., … & Kaneko, K. (2013). Evaluation of the effect of glucosamine administration on biomarkers of cartilage and bone metabolism in bicycle racers. Molecular medicine reports, 7(3), 742-746.
Ostojic, S. M., Arsic, M., Prodanovic, S., Vukovic, J., & Zlatanovic, M. (2007). Glucosamine administration in athletes: effects on recovery of acute knee injury. Research in Sports Medicine, 15(2), 113-124.
Kim LS, Axelrod LJ, Howard P, Buratovich N, Waters RF. Efficacy of methylsulfonylmethane (MSM) in osteoarthritis pain of the knee: a pilot clinical trial. Osteoarthritis Cartilage. 2006 Mar;14(3):286-94. doi: 10.1016/j.joca.2005.10.003. Epub 2005 Nov 23. PMID: 16309928.
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Tennent DJ, Hylden CM, Kocher BK, Aden JK, Johnson AE. A randomized controlled trial evaluating methylsulfonylmethane versus placebo to prevent knee pain in military initial entry trainees. US Army Med Dep J. 2017 Oct-Dec;(3-17):21-25. PMID: 29214616.
Withee ED, Tippens KM, Dehen R, Tibbitts D, Hanes D, Zwickey H. Effects of Methylsulfonylmethane (MSM) on exercise-induced oxidative stress, muscle damage, and pain following a half-marathon: a double-blind, randomized, placebo-controlled trial. J Int Soc Sports Nutr. 2017 Jul 21;14:24. doi: 10.1186/s12970-017-0181-z. PMID: 28736511; PMCID: PMC5521097.
Debbi EM, Agar G, Fichman G, Ziv YB, Kardosh R, Halperin N, Elbaz A, Beer Y, Debi R. Efficacy of methylsulfonylmethane supplementation on osteoarthritis of the knee: a randomized controlled study. BMC Complement Altern Med. 2011 Jun 27;11:50. doi: 10.1186/1472-6882-11-50. PMID: 21708034; PMCID: PMC3141601.
Daily JW, Yang M, Park S. Efficacy of Turmeric Extracts and Curcumin for Alleviating the Symptoms of Joint Arthritis: A Systematic Review and Meta-Analysis of Randomized Clinical Trials. J Med Food. 2016 Aug;19(8):717-29. doi: 10.1089/jmf.2016.3705. PMID: 27533649; PMCID: PMC5003001.
Chin KY. The spice for joint inflammation: anti-inflammatory role of curcumin in treating osteoarthritis. Drug Des Devel Ther. 2016 Sep 20;10:3029-3042. doi: 10.2147/DDDT.S117432. PMID: 27703331; PMCID: PMC5036591.
Zhang Y, Zeng Y. Curcumin reduces inflammation in knee osteoarthritis rats through blocking TLR4 /MyD88/NF-κB signal pathway. Drug Dev Res. 2019 May;80(3):353-359. doi: 10.1002/ddr.21509. Epub 2019 Jan 21. PMID: 30663793.
Perkins K, Sahy W, Beckett RD. Efficacy of Curcuma for Treatment of Osteoarthritis. J Evid Based Complementary Altern Med. 2017 Jan;22(1):156-165. doi: 10.1177/2156587216636747. Epub 2016 Mar 14. PMID: 26976085; PMCID: PMC5871206.
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Siddiqui MZ. Boswellia serrata, a potential antiinflammatory agent: an overview. Indian J Pharm Sci. 2011 May;73(3):255-61. doi: 10.4103/0250-474X.93507. PMID: 22457547; PMCID: PMC3309643.
Majeed M, Majeed S, Narayanan NK, Nagabhushanam K. A pilot, randomized, double-blind, placebo-controlled trial to assess the safety and efficacy of a novel Boswellia serrata extract in the management of osteoarthritis of the knee. Phytother Res. 2019 May;33(5):1457-1468. doi: 10.1002/ptr.6338. Epub 2019 Mar 6. PMID: 30838706; PMCID: PMC6681146.
Kimmatkar N, Thawani V, Hingorani L, Khiyani R. Efficacy and tolerability of Boswellia serrata extract in treatment of osteoarthritis of knee–a randomized double blind placebo controlled trial. Phytomedicine. 2003 Jan;10(1):3-7. doi: 10.1078/094471103321648593. PMID: 12622457.
Yu G, Xiang W, Zhang T, Zeng L, Yang K, Li J. Effectiveness of Boswellia and Boswellia extract for osteoarthritis patients: a systematic review and meta-analysis. BMC Complement Med Ther. 2020 Jul 17;20(1):225. doi: 10.1186/s12906-020-02985-6. PMID: 32680575; PMCID: PMC7368679.
Salwowska NM, Bebenek KA, Żądło DA, Wcisło-Dziadecka DL. Physiochemical properties and application of hyaluronic acid: a systematic review. J Cosmet Dermatol. 2016 Dec;15(4):520-526. doi: 10.1111/jocd.12237. Epub 2016 Jun 21. PMID: 27324942.
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Ricci M, Micheloni GM, Berti M, Perusi F, Sambugaro E, Vecchini E, Magnan B. Clinical comparison of oral administration and viscosupplementation of hyaluronic acid (HA) in early knee osteoarthritis. Musculoskelet Surg. 2017 Apr;101(1):45-49. doi: 10.1007/s12306-016-0428-x. Epub 2016 Sep 28. PMID: 27681813.
60 tablets | |
Nutrition information | |
Daily dose 3 tablets | |
Servings per container:20 | |
Per daily dose (3 tablets) | |
Glucosamine | 500 mg |
MSM | 500 mg |
Curcuminoids Curcugreen™ | 237,5 mg |
Boswellia BosLIQ® of which AKBA other β-boswellic acids total diterpenes | 350 mg 10 mg 40 mg 16 mg |
Hyaluronic acid | 100 mg |
Ingredients: bulking agent: cellulose; glucosamine D-sulphate 2KCl (from shellfish), methylsulfonylmethane (MSM), Curcugreen™ [curcuminoids from turmeric rhizome (Curcuma longa L.)], BosLIQ®-AKBA-PWD ( boswellia dry extract (Boswellia sacra Flueck.) gum-resin 5% acetyl-11-keto-β-boswellic acid (AKBA), 20% other β-boswellic acids and 8% total diterpenes), sodium hyaluronate, anti-caking agents: magnesium salts of fatty acids, silicon dioxide.
Directions: take 3 tablets a day with water.
WarningsWARNINGS: do not exceed the recommended daily dose. Food supplements should not be used as a substitute of a varied diet. A varied and balanced diet and a healthy lifestyle are important. Keep out of reach of young children. Keep in a dry place away from heat sources.
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